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4-Hydroxybenzoic acid
| Product Name | 4-Hydroxybenzoic acid |
| Price: | $15 / 50mg |
| Catalog No.: | CN03942 |
| CAS No.: | 99-96-7 |
| Molecular Formula: | C7H6O3 |
| Molecular Weight: | 138.1 g/mol |
| Purity: | >=98% |
| Type of Compound: | Phenols |
| Physical Desc.: | Powder |
| Source: | The herbs of Rhodiola crenulata. |
| Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| SMILES: | Oc1ccc(cc1)C(=O)O |
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| Description | 4-Hydroxybenzoic acid, a phenolic derivative of benzoic acid, could inhibit most gram-positive and some gram-negative bacteria, with an IC50 of 160 μg/mL. |
| Target | Human Endogenous Metabolite Bacteria:160 μg/mL (IC50) |
| In Vitro | Most of the gram-positive and some gram-negative bacteria are sensitive to trans 4-Hydroxycinnamic acid (4-HBA) and 4-Hydroxybenzoic acid at IC50 concentrations of 100-170 and 160 μg/mL, respectively. The antimicrobial activities of 4-Hydroxycinnamic acid and t4-HCA against 11 food pathogenic bacteria, 6 plant pathogenic bacteria, 2 yeasts and 15 plant pathogenic fungi are tested by the paper disc method. These compounds inhibit the growth of most of the bacteria and yeasts at concentrations of 200-400 μg. However, the inhibition is more effective against most of the gram-positive bacteria. When tested by the paper disc method, 4-Hydroxycinnamic acid has stronger antimicrobial activity than t4-HCA against S. aureus, L. mesenteroides, S. cerevisiae and C. albicans at a concentration of 50 μg. However, no inhibitory effect against fungi was observed at concentrations even up to 1000 μg[1]. |
| Density | 1.4±0.1 g/cm3 |
| Boiling Point | 336.2±25.0 °C at 760 mmHg |
| Flash Point | 171.3±19.7 °C |
| Exact Mass | 138.031693 |
| PSA | 57.53000 |
| LogP | 1.42 |
| Vapour Pressure | 0.0±0.8 mmHg at 25°C |
| Storage condition | Refrigerator |