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Neogambogic acid
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Product Name Neogambogic acid
Price: Inquiry
Catalog No.: CN06604
CAS No.: 93772-31-7
Molecular Formula: C38H46O9
Molecular Weight: 646.77 g/mol
Purity: >=98%
Type of Compound: Miscellaneous
Physical Desc.: Yellow cryst.
Source: The herbs of Garcinia hanburyi Hook. f.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
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Description Neogambogic acid, an active ingredient in garcinia, induces apoptosis and has anticancer effect. Neogambogic acid has significant inhibitory activity toward methicillin-resistant Staphylococcus aureus (MRSA)[1][2].
In Vitro Neogambogic acid inhibits HCT-8, Bel-7402, BGC-823, A549, and A2780 cell proliferation, with an IC50 between 1.75 and 3 μM. Neogambogic acid induces A549 cells apoptosis arrested the cells to G0/G1 phase in vitro[1].
In Vivo Neogambogic acid arrests A549-induced tumor growth in nude mice[1].
Density1.3±0.1 g/cm3
Boiling Point810.3±65.0 °C at 760 mmHg
Flash Point250.2±27.8 °C
Exact Mass646.314209
PSA139.59000
LogP8.19
Vapour Pressure0.0±3.0 mmHg at 25°C