Description |
Neogambogic acid, an active ingredient in garcinia, induces apoptosis and has anticancer effect. Neogambogic acid has significant inhibitory activity toward methicillin-resistant Staphylococcus aureus (MRSA)[1][2].
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In Vitro |
Neogambogic acid inhibits HCT-8, Bel-7402, BGC-823, A549, and A2780 cell proliferation, with an IC50 between 1.75 and 3 μM. Neogambogic acid induces A549 cells apoptosis arrested the cells to G0/G1 phase in vitro[1].
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In Vivo |
Neogambogic acid arrests A549-induced tumor growth in nude mice[1].
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Density | 1.3±0.1 g/cm3 |
Boiling Point | 810.3±65.0 °C at 760 mmHg |
Flash Point | 250.2±27.8 °C |
Exact Mass | 646.314209 |
PSA | 139.59000 |
LogP | 8.19 |
Vapour Pressure | 0.0±3.0 mmHg at 25°C |