Home
Products
Guaiacol
| Product Name | Guaiacol |
| Price: | Inquiry |
| Catalog No.: | CN03299 |
| CAS No.: | 90-05-1 |
| Molecular Formula: | C7H8O2 |
| Molecular Weight: | 124.14 g/mol |
| Purity: | >=98% |
| Type of Compound: | Phenols |
| Physical Desc.: | Oil |
| Source: | |
| Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| SMILES: | COc1ccccc1O |
| Contact us | |
|---|---|
| First Name: | |
| Last Name: | |
| E-mail: | |
| Question: | |
| Description | Guaiacol, a phenolic compound isolated from Guaiac resin, inhibits LPS-stimulated COX-2 expression and NF-κB activation[1]. Anti-inflammatory activity[1]. |
| Target | COX-2 NF-κB |
| In Vitro | Guaiacol inhibits LPS-stimulated nuclear factor kappa B (NF-κB) activation and cyclooxygenase (COX)-2 gene expression in cells of the RAW 264.7 murine macrophage cell line. Phenolic compounds such as Phenol, Eugenol, Guaiacol and Vanillin inhibit sheep vesicular gland prostaglandin cyclooxygenase, as indicated by their 50% inhibition concentrations, which decline in the following order: Phenol (1600 μM) > Vanillin (>500 μM) > Guaiacol (72 μM) > Eugenol (12 μM)[1]. |
| Density | 1.2±0.1 g/cm3 |
| Boiling Point | 207.5±29.0 °C at 760 mmHg |
| Flash Point | 79.3±24.3 °C |
| PSA | 29.46000 |
| LogP | 2.11 |
| Vapour Pressure | 0.2±0.4 mmHg at 25°C |
| Storage condition | Refrigerator |