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6-Hydroxyrubiadin
| Product Name | 6-Hydroxyrubiadin |
| Price: | $351 / 5mg |
| Catalog No.: | CN05980 |
| CAS No.: | 87686-86-0 |
| Molecular Formula: | C15H10O5 |
| Molecular Weight: | 270.2 g/mol |
| Purity: | >=98% |
| Type of Compound: | Anthraquinones |
| Physical Desc.: | Yellow powder |
| Source: | The roots of Rubia cordifolia L. |
| Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| SMILES: |
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| Description | 6-Hydroxyrubiadin, a natural anthraquinone, may be a potential therapeutic candidate for the treatment of inflammation and inflammatory diseases[1]. |
| In Vitro | 6-hydroxyrubiadin suppresses lipopolysaccharide (LPS)-induced nuclear factor-kappa B activation as well as the phosphorylation of c-Jun N-terminal kinase in RAW 264.7 macrophages[1]. 6-hydroxyrubiadin inhibited the expression of tumor necrosis factor (TNF)-a, interleukin (IL)-1b and IL-6 in phorbol myristate acetate (PMA)-primed U937 and RAW 264.7cells[1]. |
| In Vivo | 6-hydroxyrubiadin can reduce the production of pro-inflammatory cytokines and ameliorate acute lung injury (ALI) in a mouse model[1]. |
| Density | 1.6±0.1 g/cm3 |
| Boiling Point | 558.7±19.0 °C at 760 mmHg |
| Flash Point | 305.7±18.0 °C |
| Exact Mass | 270.052826 |
| PSA | 94.83000 |
| LogP | 4.42 |
| Vapour Pressure | 0.0±1.6 mmHg at 25°C |