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Product Name | Rhodiosin |
Price: | $146 / 10mg |
Catalog No.: | CN04529 |
CAS No.: | 86831-54-1 |
Molecular Formula: | C27H30O16 |
Molecular Weight: | 610.52 g/mol |
Purity: | >=98% |
Type of Compound: | Flavonoids |
Physical Desc.: | Powder |
Source: | The herbs of Rhodiola rosea L. |
Solvent: | DMSO, Pyridine, Methanol, Ethanol, etc. |
SMILES: | OC[C@H]1O[C@@H](O[C@H]2[C@@H](O)[C@@H](O[C@H]([C@@H]2O)C)Oc2cc(O)c3c(c2O)oc(c(c3=O)O)c2ccc(cc2)O)[C@@H]([C@H]([C@@H]1O)O)O |
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Description | Rhodiosin, isolated from the root of Rhodiola crenulata, is a specific non-competitive cytochrome P450 2D6 inhibitor with an IC50 of 0.420 μM and a Ki of 0.535 μM[1]. Rhodiosin exhibits potent, dose-dependent inhibitory effects on acetylcholinesterase (AChE) with IC50 ranged from 57.50 to 2.43 μg/mL[2]. Rhodiosin exhibits potent DPPH free radical scavenging activities, with an IC50 of 27.77 μM[3]. |
Target | IC50: 0.420 μM (cytochrome P450 2D6)[1];57.50-2.43 μg/mL (AChE)[2];27.77 μM (DPPH free radical scavenging)[3] |
Density | 1.8±0.1 g/cm3 |
Boiling Point | 994.3±65.0 °C at 760 mmHg |
Flash Point | 329.1±27.8 °C |
Exact Mass | 610.153381 |
PSA | 269.43000 |
LogP | -2.25 |
Vapour Pressure | 0.0±0.3 mmHg at 25°C |