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5,8-Epidioxyergosta-6,9(11),22-trien-3-ol
| Product Name | 5,8-Epidioxyergosta-6,9(11),22-trien-3-ol |
| Price: | Inquiry |
| Catalog No.: | CN02418 |
| CAS No.: | 86363-50-0 |
| Molecular Formula: | C28H42O3 |
| Molecular Weight: | 426.63 g/mol |
| Purity: | >=98% |
| Type of Compound: | Steroids |
| Physical Desc.: | Powder |
| Source: | The fruitbody of Ganoderma lucidum |
| Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| SMILES: |
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| Description | 5,8-Epidioxyergosta-6,9(11),22-trien-3-ol (9,11-Dehydroergosterol peroxide), an important steroid from medicinal mushroom, exerts antitumor activity in several tumor types. 5,8-Epidioxyergosta-6,9(11),22-trien-3-ol inhibits HT29 cell growth by inducing CDKN1A expression, thus causing cell cycle arrest and apoptosis[1][2]. |
| Target | Microbial Metabolite |
| In Vitro | 5,8-Epidioxyergosta-6,9(11),22-trien-3-ol (9,11-Dehydroergosterol peroxide) is an effective inhibitor of HL60 leukemia cell growth and apoptosis-inducer[1]. Apoptosis induced by 5,8-Epidioxyergosta-6,9(11),22-trien-3-ol from Ganoderma Lucidum mycelium in human malignant melanoma cells is Mcl‑1 dependent[2]. |
| Exact Mass | 426.31300 |
| PSA | 38.69000 |
| LogP | 6.39370 |