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Rhodionin
| Product Name | Rhodionin |
| Price: | Inquiry |
| Catalog No.: | CN05490 |
| CAS No.: | 85571-15-9 |
| Molecular Formula: | C21H20O11 |
| Molecular Weight: | 448.38 g/mol |
| Purity: | >=98% |
| Type of Compound: | Flavonoids |
| Physical Desc.: | Yellow powder |
| Source: | The herbs of Rhodiola rosea |
| Solvent: | DMSO, Pyridine, Methanol, Ethanol, etc. |
| SMILES: | OC1C(OC(C(C1O)O)C)Oc1cc(O)c2c(c1O)oc(c(c2=O)O)c1ccc(cc1)O |
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| Description | Rhodionin, isolated from the root of Rhodiola crenulata, is a specific non-competitive cytochrome P450 2D6 inhibitor with an IC50 of 0.761 μM and a Ki of 0.769 μM[1]. Rhodionin exhibits potent, dose-dependent inhibitory effects on acetylcholinesterase (AChE) with IC50 ranged from 57.50 to 2.43 μg/mL[2]. Rhodionin exhibits potent DPPH free radical scavenging activities, with an IC50 of 19.49 μM[3]. |
| Target | IC50: 0.761 μM (cytochrome P450 2D6)[1]；57.50-2.43 μg/mL (AChE)[2]；19.49 μM (DPPH free radical scavenging)[3] |
| Density | 1.7±0.1 g/cm3 |
| Boiling Point | 802.9±65.0 °C at 760 mmHg |
| Flash Point | 284.4±27.8 °C |
| Exact Mass | 448.100555 |
| PSA | 190.28000 |
| LogP | 0.44 |
| Vapour Pressure | 0.0±3.0 mmHg at 25°C |
| Storage condition | 2-8℃ |