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Product Name | Isoastragaloside I |
Price: | $204 / 10mg |
Catalog No.: | CN07505 |
CAS No.: | 84676-88-0 |
Molecular Formula: | C45H72O16 |
Molecular Weight: | 869.1 g/mol |
Purity: | >=98% |
Type of Compound: | Triterpenoids |
Physical Desc.: | Powder |
Source: | The roots of Astragalus membranaceus |
Solvent: | DMSO, Pyridine, Methanol, Ethanol, etc. |
SMILES: | OC[C@H]1O[C@@H](O[C@H]2C[C@H]3[C@]4(C)C[C@@H]([C@@H]([C@@]4(C)CC[C@]43[C@@]3([C@@H]2C(C)(C)[C@H](CC3)O[C@@H]2OC[C@H]([C@@H]([C@H]2OC(=O)C)O)OC(=O)C)C4)[C@@]2(C)CC[C@H](O2)C(O)(C)C)O)[C@@H]([C@H]([C@@H]1O)O)O |
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Description | Isoastragaloside I is a natural compound from the medicinal herb Radix Astragali; possesses the activity of elevating adiponectin production.IC50 value:Target:Astragaloside II and isoastragaloside I selectively increased adiponectin secretion in primary adipocytes without any obvious effects on a panel of other adipokines. Furthermore, an additive effect on induction of adiponectin production was observed between these two compounds and rosiglitazone, a thiazolidinedione class of insulin-sensitizing drugs. Chronic administration of astragaloside II and isoastragaloside I in both dietary and genetic obese mice significantly elevated serum levels of total adiponectin and selectively increased the composition of its high molecular weight oligomeric complex. |
Density | 1.4±0.1 g/cm3 |
Boiling Point | 920.6±65.0 °C at 760 mmHg |
Flash Point | 264.7±27.8 °C |
Exact Mass | 868.482056 |
PSA | 240.36000 |
LogP | 2.03 |
Vapour Pressure | 0.0±0.6 mmHg at 25°C |
Storage condition | -20°C |