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Product Name | Humantenmine |
Price: | $263 / 10mg |
Catalog No.: | CN01474 |
CAS No.: | 82354-38-9 |
Molecular Formula: | C19H22N2O3 |
Molecular Weight: | 326.4 g/mol |
Purity: | >=98% |
Type of Compound: | Alkaloids |
Physical Desc.: | Powder |
Source: | The roots of Gelsemium elegans |
Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
SMILES: | CON1c2ccccc2[C@@]2(C1=O)C[C@@H]1N=C([C@H]3C[C@@H]2OC[C@H]13)CC |
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Description | Humantenmine, a newalkaloid isolated from Gelsemium elegan Banth in China, has the potential for pain and rheumatic arthritis treatment[1][2]. |
In Vitro | Humantenmine (HMT) decreases the 14-day survival rate of the mice to 17% after they are intragastrically treated with HMT, along with hepatic injury and increasing alanine aminotransferase (ALT)/aspartate aminotransferase (AST) levels. CYP3A4/5 mediates the metabolism and detoxification of HMT[1][2]. |
Density | 1.4±0.1 g/cm3 |
Boiling Point | 463.6±55.0 °C at 760 mmHg |
Flash Point | 234.2±31.5 °C |
Exact Mass | 326.163055 |
PSA | 51.13000 |
LogP | 3.68 |
Vapour Pressure | 0.0±1.1 mmHg at 25°C |