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Khellin
| Product Name | Khellin |
| Price: | $43 / 50mg |
| Catalog No.: | CN05246 |
| CAS No.: | 82-02-0 |
| Molecular Formula: | C14H12O5 |
| Molecular Weight: | 260.2 g/mol |
| Purity: | >=98% |
| Type of Compound: | Flavonoids |
| Physical Desc.: | Yellow powder |
| Source: | The herbs of Ammi visnaga. |
| Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| SMILES: | COc1c2c(=O)cc(oc2c(c2c1cco2)OC)C |
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| Description | Khellin, a naturally occurring furochromone, is an EGFR inhibitor with an IC50 of 0.15 µM. Khelline has anti-proliferative activity in vitro. Khellin has antispasmodic and coronary vasodilator effects[1][2]. |
| Target | IC50: 0.15 µM (EGFR)[1] |
| In Vitro | Khelline exhibits anti-proliferative activity for MCF-7 cells and Hela cells[1]. Khellin causes total relaxation of both NA- and K+-contractions and a change in external calcium concentration[2]. |
| Density | 1.3±0.1 g/cm3 |
| Boiling Point | 482.1±0.0 °C at 760 mmHg |
| Flash Point | 218.8±28.7 °C |
| Exact Mass | 260.068481 |
| PSA | 61.81000 |
| LogP | 1.77 |
| Vapour Pressure | 0.0±1.2 mmHg at 25°C |