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Ganoderic acid A
| Product Name | Ganoderic acid A |
| Price: | $161 / 20mg |
| Catalog No.: | CN07731 |
| CAS No.: | 81907-62-2 |
| Molecular Formula: | C30H44O7 |
| Molecular Weight: | 516.7 g/mol |
| Purity: | >=98% |
| Type of Compound: | Triterpenoids |
| Physical Desc.: | Powder |
| Source: | The fruit body of Ganoderma lucidum. |
| Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| SMILES: | O=C(C[C@H](C(=O)O)C)C[C@H]([C@H]1C[C@@H]([C@@]2([C@]1(C)CC(=O)C1=C2[C@@H](O)CC2[C@]1(C)CCC(=O)C2(C)C)C)O)C |
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| Description | Ganoderic acid can Inhibitt of the JAK-STAT3 signaling pathway, also inhibit proliferation, viability, ROS.In vitro: A lower doses of Ganoderic acid enhance HLA class II-mediated antigen presentation and CD4+ T cell recognition of lymphoma. [1] ganoderic acid A promots cisplatin-induced cell death by enhancing the sensitivity of HepG2 cells to cisplatin mainly via the signal transducer and activator of transcription 3 suppression. [2] Ganoderic acid A inhibits proliferation, viability, ROS, DPPH, and analyzed the expression of SOD1, SOD2, and SOD3 by Real time PCR in a PC-3 cell in a dose-dependent manner.[3] GA-A effectively inhibites the proliferation of human osteosarcoma HOS and MG-63 cells in a dose-dependent manner, and induced obvious cell apoptosis in both cells.[4]In vivo: Ganoderic acid -treatment significantly prolonged survival of EL4 challenged mice and decreased tumor metastasis to the liver.[1] |
| Density | 1.2±0.1 g/cm3 |
| Boiling Point | 700.3±60.0 °C at 760 mmHg |
| Flash Point | 391.3±29.4 °C |
| PSA | 128.97000 |
| LogP | 2.15 |
| Vapour Pressure | 0.0±5.0 mmHg at 25°C |
| Storage condition | -20°C |