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Sanggenone C
| Product Name | Sanggenone C |
| Price: | $351 / 20mg |
| Catalog No.: | CN05514 |
| CAS No.: | 80651-76-9 |
| Molecular Formula: | C40H36O12 |
| Molecular Weight: | 708.71 g/mol |
| Purity: | >=98% |
| Type of Compound: | Flavonoids |
| Physical Desc.: | Powder |
| Source: | The root barks of Morus alba L. |
| Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| SMILES: | CC(=CC[C@@]12Oc3cc(O)c(c(c3C(=O)[C@@]2(O)Oc2c1ccc(c2)O)O)[C@H]1C=C(C)C[C@@H]([C@H]1C(=O)c1ccc(cc1O)O)c1ccc(cc1O)O)C |
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| Description | Sanggenon C is a flavanone Diels-Alder adduct compound, which is isolated from the root bark of Morus cathayana. Sanggenon C exerts protective effects against cardiac hypertrophy and fibrosis via suppression of the calcineurin/NFAT2 pathway. Sanggenon C inhibits inducible nitric oxide synthase expression in RAW264.7 cells, and tumor necrosis factor-α-stimulated cell adhesion and vascular cell adhesion molecule-1 expression, by suppressing NF-κB activity[1]. Sanggenon C possesses antioxidant, anti-inflammatory activities and inhibits Pancreatic lipase (PL) with the an IC50 of 3.00 μM[2]. |
| Target | NF-κB |
| Density | 1.5±0.1 g/cm3 |
| Boiling Point | 999.3±65.0 °C at 760 mmHg |
| Flash Point | 312.7±27.8 °C |
| Exact Mass | 708.220703 |
| PSA | 214.44000 |
| LogP | 7.94 |
| Vapour Pressure | 0.0±0.3 mmHg at 25°C |
| Storage condition | 2-8℃ |