Home
Products
Paeoniflorigenone
| Product Name | Paeoniflorigenone |
| Price: | Inquiry |
| Catalog No.: | CN09649 |
| CAS No.: | 80454-42-8 |
| Molecular Formula: | C17H18O6 |
| Molecular Weight: | 318.3 g/mol |
| Purity: | >=98% |
| Type of Compound: | Monoterpenoids |
| Physical Desc.: | Powder |
| Source: | The roots of Paeonia lactiflora Pall. |
| Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| SMILES: |
| Contact us | |
|---|---|
| First Name: | |
| Last Name: | |
| E-mail: | |
| Question: | |
| Description | Paeoniflorigenone, isolated as an active ingredient from the root of moutan cortex, induces apoptosis selectively in the cancer cell lines and exhibits antiproliferative effect[1]. |
| In Vitro | Paeoniflorigenone (0-30 μM; 0-72 hours) significantly decreases the cell proliferation of tumor cell lines and inhibits the proliferation of normal cell lines[1]. Paeoniflorigenone (0-30 μM; 24-72 hours) significantly induces apoptotic DNA fragmentation selectively in tumor cells[1]. Cell Proliferation Assay[1] Cell Line: TIG-1, 3T3-L1, HL60, Jurkat and HeLa cells Concentration: 0-30 μM Incubation Time: 0-72 hours Result: Significantly decreased the cell proliferation of tumor cell lines and inhibited the proliferation of normal cell lines. Apoptosis Analysis[1] Cell Line: TIG-1 and 3T3-L1 (normal cells), HL60, Jurkat, and HeLa cells (tumor cells) Concentration: 0, 1, 3, 10, 30 μM Incubation Time: 24 and 72 hours Result: Induced DNA fragmentation in three tumor cell lines, but not in two normal cell lines. |
| Density | 1.4±0.1 g/cm3 |
| Boiling Point | 481.1±45.0 °C at 760 mmHg |
| Flash Point | 177.1±22.2 °C |
| Exact Mass | 318.110352 |
| PSA | 82.06000 |
| LogP | 2.87 |
| Vapour Pressure | 0.0±1.3 mmHg at 25°C |