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9-Oxo-10,11-dehydroageraphorone
| Product Name | 9-Oxo-10,11-dehydroageraphorone |
| Price: | Inquiry |
| Catalog No.: | CN09393 |
| CAS No.: | 79491-71-7 |
| Molecular Formula: | C15H20O2 |
| Molecular Weight: | 232.3 g/mol |
| Purity: | >=98% |
| Type of Compound: | Sesquiterpenoids |
| Physical Desc.: | Powder |
| Source: | The herbs of Eupatorium adenophorum |
| Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| SMILES: |
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| Description | Euptox A (9-Oxo-10, 11-dehydroageraphorone), a cadenine sesquiterpene, is the main toxin that can be isolated from Eupatorium adenophorum. Euptox A induces apoptosis by improving the gene expression level of apoptotic proteases such as caspase-10 in HeLa cells[1]. |
| In Vitro | Euptox A (0-2 μg/mL, 48 h) 有效抑制HeLa细胞增殖[1]。 Euptox A（0-50 μg/mL，24 小时）阻止细胞周期从 S 期到 G2/M 期的转变[1]。 Euptox A 在体外以剂量依赖的方式对人肺癌 A549、HeLa 和 Hep-2 细胞系表现出显着的抗肿瘤活性[1]。 Euptox A 在体外对 S.scabiei 和P. cuniculi 表现出高度杀螨活性[1]。 |
| Density | 1.0±0.1 g/cm3 |
| Boiling Point | 373.9±42.0 °C at 760 mmHg |
| Flash Point | 140.3±24.9 °C |
| Exact Mass | 232.146332 |
| PSA | 34.14000 |
| LogP | 2.28 |
| Vapour Pressure | 0.0±0.8 mmHg at 25°C |