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Polygalasaponin XXXI
| Product Name | Polygalasaponin XXXI |
| Price: | $351 / 5mg |
| Catalog No.: | CN07552 |
| CAS No.: | 79103-90-5 |
| Molecular Formula: | C75H112O36 |
| Molecular Weight: | 1589.67 g/mol |
| Purity: | >=98% |
| Type of Compound: | Triterpenoids |
| Physical Desc.: | Powder |
| Source: | The herbs of Polygala japonica Houtt. |
| Solvent: | DMSO, Pyridine, Methanol, Ethanol, etc. |
| SMILES: | OCC1OC(OC2C(O)CC3(C(C2(C)C(=O)O)CCC2(C3CC=C3C2(CO)CCC2(C3CC(C)(C)CC2)C(=O)OC2OC(C)C(C(C2OC2OC(C)C(C(C2O)OC2OCC(C2O)(O)CO)OC2OCC(C(C2O)OC2OCC(C(C2O)O)O)O)O)OC(=O)C=Cc2cc(OC)c(c(c2)OC)OC)C)C)C(C(C1O)O)O |
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| Description | Polygalasaponin XXXI (Onjisaponin F) is an effective adjuvant for intranasal administration of influenza Influenza hemagglutinin (HA) vaccine to protect influenza virus infection[1]. |
| In Vitro | Polygalasaponin XXXI (Onjisaponin F) also enhances anti-HA IgA and IgG Ab titers in the nasal wash, whereas Onjisaponins E and G enhances only anti-HA IgA Ab titer significantly. Polygalasaponin XXXI can induce protective immunity against intranasal infection by influenza virus[1]. Polygalasaponin XXXI (Onjisaponin F) (1 or 10 µg/mL) also induces ChAT mRNA level in rat basal forebrain cells[2]. |
| In Vivo | Intranasal vaccination with Polygalasaponin XXXI (Onjisaponin F) inhibits proliferation of mouse adapted influenza virus A/PR/8/34 in bronchoalveolar lavages of infected mice[1]. |
| Density | 1.5±0.1 g/cm3 |
| Exact Mass | 1588.693359 |
| PSA | 542.80000 |
| LogP | 4.95 |