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Kuwanon H
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Product Name Kuwanon H
Price: $146 / 5mg
Catalog No.: CN04811
CAS No.: 76472-87-2
Molecular Formula: C45H44O11
Molecular Weight: 760.8 g/mol
Purity: >=98%
Type of Compound: Flavonoids
Physical Desc.: Yellow powder
Source: The root barks of Morus alba L.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
SMILES: CC(=CCc1c(O)ccc(c1O)C(=O)[C@H]1[C@@H](CC(=C[C@@H]1c1c(O)cc(c2c1oc(c1ccc(cc1O)O)c(c2=O)CC=C(C)C)O)C)c1ccc(cc1O)O)C
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Description Kuwanon H is a flavonoid isolated from Morus bombycis, which acts as a potent non-peptide bombesin receptor antagonist. Kuwanon H selectively inhibits binding of gastrin releasing peptide CRP to GRP-preferring recepotr, with a Ki value of 290 nM in cells[1].
Target Ki: 290 nM (GRP-preferring recepotr)[1]
Density1.371g/cm3
Boiling Point969.8ºC at 760 mmHg
Flash Point292.5ºC
Exact Mass760.28800
PSA209.12000
LogP8.83870