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Product Name | Kuwanon H |
Price: | $146 / 5mg |
Catalog No.: | CN04811 |
CAS No.: | 76472-87-2 |
Molecular Formula: | C45H44O11 |
Molecular Weight: | 760.8 g/mol |
Purity: | >=98% |
Type of Compound: | Flavonoids |
Physical Desc.: | Yellow powder |
Source: | The root barks of Morus alba L. |
Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
SMILES: | CC(=CCc1c(O)ccc(c1O)C(=O)[C@H]1[C@@H](CC(=C[C@@H]1c1c(O)cc(c2c1oc(c1ccc(cc1O)O)c(c2=O)CC=C(C)C)O)C)c1ccc(cc1O)O)C |
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Description | Kuwanon H is a flavonoid isolated from Morus bombycis, which acts as a potent non-peptide bombesin receptor antagonist. Kuwanon H selectively inhibits binding of gastrin releasing peptide CRP to GRP-preferring recepotr, with a Ki value of 290 nM in cells[1]. |
Target | Ki: 290 nM (GRP-preferring recepotr)[1] |
Density | 1.371g/cm3 |
Boiling Point | 969.8ºC at 760 mmHg |
Flash Point | 292.5ºC |
Exact Mass | 760.28800 |
PSA | 209.12000 |
LogP | 8.83870 |