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Mosloflavone
| Product Name | Mosloflavone |
| Price: | $92 / 10mg |
| Catalog No.: | CN04749 |
| CAS No.: | 740-33-0 |
| Molecular Formula: | C17H14O5 |
| Molecular Weight: | 298.3 g/mol |
| Purity: | >=98% |
| Type of Compound: | Flavonoids |
| Physical Desc.: | Yellow powder |
| Source: | The herbs of Mosla soochouensis Matsuda |
| Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| SMILES: | COc1cc2oc(cc(=O)c2c(c1OC)O)c1ccccc1 |
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| Description | Mosloflavone is a flavonoid isolated from Scutellaria baicalensis Georgi with anti-EV71 activity. Mosloflavone inhibits VP2 virus replication and protein expression during the initial stage of virus infection and inhibits viral VP2 capsid protein synthesis. Mosloflavone is a promising biocide and inhibits P. aeruginosa virulence and biofilm formation. |
| Target | IC50: EV71; bacterial[1][2] |
| In Vitro | Mosloflavone shows promising anti-inflammatory activity via inhibition of TNF-α and IL-1β with IC50 values of 16.4 uM and 6.4 uM, respectively; inhibits TNF-α, IL-1β and iNOS levels in the supernatant of mouse macrophage cell line J774A as a dose-dependent manner, it also can be used as a starting point to discover lead structures for treatment of inflammatory and immunomodulatory diseases[2]. |
| Density | 1.3±0.1 g/cm3 |
| Boiling Point | 508.5±50.0 °C at 760 mmHg |
| Flash Point | 190.5±23.6 °C |
| Exact Mass | 298.084137 |
| PSA | 68.90000 |
| LogP | 2.74 |
| Vapour Pressure | 0.0±1.4 mmHg at 25°C |