Home
Products
Broussonin A
| Product Name | Broussonin A |
| Price: | Inquiry |
| Catalog No.: | CN03938 |
| CAS No.: | 73731-87-0 |
| Molecular Formula: | C16H18O3 |
| Molecular Weight: | 258.32 g/mol |
| Purity: | >=98% |
| Type of Compound: | Phenols |
| Physical Desc.: | Powder |
| Source: | The branches of Broussonetia papyrifera |
| Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| SMILES: |
| Contact us | |
|---|---|
| First Name: | |
| Last Name: | |
| E-mail: | |
| Question: | |
| Description | Broussonin A is a potent BChE inhibitor, with an IC50 of 4.16 µM. Broussonin A is a diarylpropane natural product that can be isolated from the bark of Broussonetia papyrifera after solid fermentation[1][2][3]. |
| Target | BChE:4.16 μM (IC50) |
| In Vitro | Broussonin A（0.1-10 µM，30 分钟）通过调节细胞周期相关蛋白的表达和视网膜母细胞瘤蛋白的磷酸化状态来抑制 VEGF-A 刺激的内皮细胞增殖[1]。 Broussonin A（0-10 µM，30 分钟）消除 VEGF-A 刺激的血管生成反应，包括大鼠主动脉环的内皮细胞迁移、侵袭、管形成和微血管形成[1]。 |
| Density | 1.2±0.1 g/cm3 |
| Boiling Point | 439.5±35.0 °C at 760 mmHg |
| Flash Point | 219.6±25.9 °C |
| Exact Mass | 258.125580 |
| PSA | 49.69000 |
| LogP | 3.65 |
| Vapour Pressure | 0.0±1.1 mmHg at 25°C |