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Deoxynojirimycin hydrochloride
| Product Name | Deoxynojirimycin hydrochloride |
| Price: | Inquiry |
| Catalog No.: | CN06590 |
| CAS No.: | 73285-50-4 |
| Molecular Formula: | C6H14ClNO4 |
| Molecular Weight: | 199.6 g/mol |
| Purity: | >=98% |
| Type of Compound: | Miscellaneous |
| Physical Desc.: | Powder |
| Source: | The root barks of Morus alba L. |
| Solvent: | DMSO, Pyridine, Methanol, Ethanol, etc. |
| SMILES: | OC[C@H]1NC[C@@H]([C@H]([C@@H]1O)O)O.Cl |
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| Description | 1-Deoxynojirimycin hydrochloride (Duvoglustat hydrochloride) is a potent and orally active α-glucosidase inhibitor. 1-Deoxynojirimycin hydrochloride suppresses postprandial blood glucose and is widely used for diabetes mellitus. 1-Deoxynojirimycin hydrochloride possesses antihyperglycemic, anti-obesity, and antiviral features[1][2]. |
| In Vivo | 1-Deoxynojirimycin hydrochloride (Duvoglustat hydrochloride) (20-80 mg/kg; i.v.; daily for four weeks) shows anti-obesity effect [3]. 1-Deoxynojirimycin hydrochloride significantly improves insulin sensitivity via activating insulin signaling PI3K/AKT pathway in skeletal muscle of db/db mice[3]. Animal Model: db/db mice[3] Dosage: 20, 40, 80 mg/kg Administration: Intravenously; daily for four weeks Result: Significantly reduced body weight, blood glucose and serum insulin levels; Improved glucose tolerance and insulin tolerance. |
| Density | 1.456 g/cm3 |
| Boiling Point | 361.1ºC at 760 mmHg |
| Flash Point | 197.3ºC |
| Exact Mass | 199.061142 |
| PSA | 92.95000 |