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Product Name | 2',3'-Dihydroxy-4'-methoxyacetophenone |
Price: | Inquiry |
Catalog No.: | CN03647 |
CAS No.: | 708-53-2 |
Molecular Formula: | C9H10O4 |
Molecular Weight: | 182.17 g/mol |
Purity: | >=98% |
Type of Compound: | Phenols |
Physical Desc.: | Powder |
Source: | The herbs of Cynenchum paniculatum. |
Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
SMILES: | COc1ccc(c(c1O)O)C(=O)C |
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Description | 2,3-Dihydroxy-4-methoxyacetophenone is a neuroprotective compound from Cynenchum paniculatum. 2,3-Dihydroxy-4-methoxyacetophenone improves cognitive function and may has the potential for the treatment of Alzheimer's disease research[1]. |
In Vitro | 2,3-Dihydroxy-4-methoxyacetophenone protects HT22 cells on glutamate induced cell-death in a dose-dependent manner (EC50=10.94 μM). 2,3-Dihydroxy-4-methoxyacetophenone inhibits [Ca2+] accumulation in HT22 cells and has antioxidantive activity[1]. |
In Vivo | 2,3-dihydroxy-4-methoxyacetophenone (50mg/kg; po) improves the impairment of spatial memory induced by scopolamine[1]. |
Density | 1.3±0.1 g/cm3 |
Boiling Point | 359.6±42.0 °C at 760 mmHg |
Flash Point | 147.7±21.4 °C |
Exact Mass | 182.057907 |
PSA | 66.76000 |
LogP | 1.81 |
Vapour Pressure | 0.0±0.8 mmHg at 25°C |