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2',3'-Dihydroxy-4'-methoxyacetophenone
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Product Name 2',3'-Dihydroxy-4'-methoxyacetophenone
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Catalog No.: CN03647
CAS No.: 708-53-2
Molecular Formula: C9H10O4
Molecular Weight: 182.17 g/mol
Purity: >=98%
Type of Compound: Phenols
Physical Desc.: Powder
Source: The herbs of Cynenchum paniculatum.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
SMILES: COc1ccc(c(c1O)O)C(=O)C
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Description 2,3-Dihydroxy-4-methoxyacetophenone is a neuroprotective compound from Cynenchum paniculatum. 2,3-Dihydroxy-4-methoxyacetophenone improves cognitive function and may has the potential for the treatment of Alzheimer's disease research[1].
In Vitro 2,3-Dihydroxy-4-methoxyacetophenone protects HT22 cells on glutamate induced cell-death in a dose-dependent manner (EC50=10.94 μM). 2,3-Dihydroxy-4-methoxyacetophenone inhibits [Ca2+] accumulation in HT22 cells and has antioxidantive activity[1].
In Vivo 2,3-dihydroxy-4-methoxyacetophenone (50mg/kg; po) improves the impairment of spatial memory induced by scopolamine[1].
Density1.3±0.1 g/cm3
Boiling Point359.6±42.0 °C at 760 mmHg
Flash Point147.7±21.4 °C
Exact Mass182.057907
PSA66.76000
LogP1.81
Vapour Pressure0.0±0.8 mmHg at 25°C