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Product Name | Obtusin |
Price: | $117 / 5mg |
Catalog No.: | CN05943 |
CAS No.: | 70588-05-5 |
Molecular Formula: | C18H16O7 |
Molecular Weight: | 344.31 g/mol |
Purity: | >=98% |
Type of Compound: | Anthraquinones |
Physical Desc.: | Powder |
Source: | The seeds of Cassia obtusifolia L. |
Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
SMILES: | COc1c(OC)cc2c(c1O)C(=O)c1c(C2=O)cc(c(c1OC)O)C |
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Description | Obtusin, isolated from Cassia obtusifolia Linn seed, is a highly selective and competitive human monoamine oxidase-A (hMAO-A) inhibitor with an IC50 of 11.12 μM and a Ki of 6.15. Obtusin plays a preventive role in neurodegenerative diseases, especially anxiety and depression[1]. |
Target | IC50: 11.12 μM (hMAO-A)[1] Ki: 6.15 (hMAO-A)[1] |
Density | 1.4±0.1 g/cm3 |
Boiling Point | 614.9±55.0 °C at 760 mmHg |
Flash Point | 227.0±25.0 °C |
Exact Mass | 344.089600 |
PSA | 102.29000 |
LogP | 4.10 |
Vapour Pressure | 0.0±1.8 mmHg at 25°C |
Storage condition | 2-8℃ |