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Product Name | Physalin H |
Price: | Inquiry |
Catalog No.: | CN02360 |
CAS No.: | 70241-09-7 |
Molecular Formula: | C28H31ClO10 |
Molecular Weight: | 562.99 g/mol |
Purity: | >=98% |
Type of Compound: | Steroids |
Physical Desc.: | Powder |
Source: | The herbs of Physalis alkekengi. |
Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
SMILES: |
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Description | Physalin H is a natural product that can be isolated from Solanum nigrum. Physalin H is an inhibitor of Hedgehog (Hh) signaling and it disrupts GLI1-DNA-complex formation. Physalin H inhibits GLI1 transcription with an IC50 value of 0.7 μM. Physalin H shows cytotoxicity to PANC1 and DU145 cells with IC50 values of 5.7 and 6.8 μM, respectively[1]. |
Density | 1.59g/cm3 |
Exact Mass | 562.16100 |
PSA | 145.66000 |
LogP | 0.96910 |