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Physalin H
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Product Name Physalin H
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Catalog No.: CN02360
CAS No.: 70241-09-7
Molecular Formula: C28H31ClO10
Molecular Weight: 562.99 g/mol
Purity: >=98%
Type of Compound: Steroids
Physical Desc.: Powder
Source: The herbs of Physalis alkekengi.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
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Description Physalin H is a natural product that can be isolated from Solanum nigrum. Physalin H is an inhibitor of Hedgehog (Hh) signaling and it disrupts GLI1-DNA-complex formation. Physalin H inhibits GLI1 transcription with an IC50 value of 0.7 μM. Physalin H shows cytotoxicity to PANC1 and DU145 cells with IC50 values of 5.7 and 6.8 μM, respectively[1].
Density1.59g/cm3
Exact Mass562.16100
PSA145.66000
LogP0.96910