Home
Products
Harpagide
| Product Name | Harpagide |
| Price: | Inquiry |
| Catalog No.: | CN03160 |
| CAS No.: | 6926-08-5 |
| Molecular Formula: | C15H24O10 |
| Molecular Weight: | 364.35 g/mol |
| Purity: | >=98% |
| Type of Compound: | Iridoids |
| Physical Desc.: | White powder |
| Source: | The roots of Scrophularia ningpoensis Hemsl. |
| Solvent: | DMSO, Pyridine, Methanol, Ethanol, etc. |
| SMILES: | OC[C@H]1O[C@@H](O[C@@H]2OC=C[C@@]3(C2[C@@](C)(O)C[C@H]3O)O)[C@@H]([C@H]([C@@H]1O)O)O |
| Contact us | |
|---|---|
| First Name: | |
| Last Name: | |
| E-mail: | |
| Question: | |
| Description | Harpagide is a class of iridoid glycoside isolated from Scrophularia cryptophila and has antiparasitic activity, which exhibits good in vitro trypanocidal activities against African trypanosomes (T.b. rhodesiense) with an IC50 of 21 μg/mL. Harpagide exerts significant antileishmanial activity against L. donovani with an IC50 value of 2.0 μg/mL. Harpagide also possess significant anti-inflammatory activities[1][2]. |
| In Vitro | Harpagide shows cytotoxic activity over 50% in a concentration of 90 μg/mL, Harpagide on the A431 and HeLa cell lines. The cytotoxic effect of Harpagide on the MCF7 cell line in a concentration of 90 μg/mL[3]. |
| Density | 1.7±0.1 g/cm3 |
| Boiling Point | 637.1±55.0 °C at 760 mmHg |
| Flash Point | 339.1±31.5 °C |
| Exact Mass | 364.136932 |
| PSA | 169.30000 |
| LogP | -3.69 |
| Vapour Pressure | 0.0±4.3 mmHg at 25°C |