Home
Products
Moracin D
| Product Name | Moracin D |
| Price: | Inquiry |
| Catalog No.: | CN03980 |
| CAS No.: | 69120-07-6 |
| Molecular Formula: | C19H16O4 |
| Molecular Weight: | 308.3 g/mol |
| Purity: | >=98% |
| Type of Compound: | Phenols |
| Physical Desc.: | Powder |
| Source: | The root barks of Morus alba L. |
| Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| SMILES: |
| Contact us | |
|---|---|
| First Name: | |
| Last Name: | |
| E-mail: | |
| Question: | |
| Description | Moracin D is a flavonoid that can be isolated from Morus alba. Moracin D induces cell apoptosis and shows hypoglycemic, antiadipogenic, antifungal and antitumor effects. Moracin D can be used for fungal infection and breast cancer research[1][2][3]. |
| In Vitro | Moracin D (0，3.75，7.5，15，30 μM；24 小时) 降低 DU145 和 PC3 细胞的活力，IC50 分别为 15 和 24.8 μM[1]。 Moracin D (0，7.5，15 μM；24 小时) 增加 DU145 和 PC3 前列腺癌细胞的 sub G1 细胞群[1]。 Moracin D (0，7.5，15 μM；24 小时) 抑制抗凋亡蛋白的表达水平，增加 DU145 细胞的 TUNEL 阳性细胞数，诱导 DU145 细胞凋亡[1]。 Moracin D 对玫瑰镰刀菌、赤霉病菌、茄病菌、赤霉病菌、森氏刺头菌、黑蔷薇菌和麻斑病菌有抑菌活性，MIC 值分别为 7-14，28-56，112，7-14，56-112，<3.5 和 14-28 μg/mL[2]。 Cell Viability Assay[1] Cell Line: DU145 and PC3 cell lines Concentration: 0, 3.75, 7.5, 15 and 30 μM Incubation Time: 24 hours Result: Significantly and dose-dependently reduced the viability of DU145 and PC3 cells. Western Blot Analysis[1] Cell Line: DU145 cell line Concentration: 0, 7.5 and 15 μM Incubation Time: 24 hours Result: Cleaved PARP, activated PPAR-γ/PKC-δ, and decreased the level of Pro-caspase 3, Bcl-2, Bcl-xL, PKC-α and phosphorylation of NF-κB, ERK, AKT in DU145 cells. |
| Density | 1.3±0.1 g/cm3 |
| Boiling Point | 419.1±45.0 °C at 760 mmHg |
| Flash Point | 207.3±28.7 °C |
| Exact Mass | 308.104858 |
| PSA | 62.83000 |
| LogP | 5.05 |
| Vapour Pressure | 0.0±1.0 mmHg at 25°C |