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Product Name | Xanthohumol I |
Price: | Inquiry |
Catalog No.: | CN05622 |
CAS No.: | 688360-06-7 |
Molecular Formula: | C21H22O6 |
Molecular Weight: | 370.40 g/mol |
Purity: | >=98% |
Type of Compound: | Chalcones |
Physical Desc.: | Powder |
Source: | The herbs of Humulus lupulus |
Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
SMILES: |
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Description | Xanthohumol I, a chalkone, is a derivative of Xanthohumol (HY-N1067). Xanthohumol is a Cholinesterase (ChE) inhibitor, which inhibits acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) wih IC50s of 71.34 μM and 32.67 μM, respectively. The hydroxy compound of Xanthohumol (3-hydroxy-xanthohumol), also shoes inhibitory effect on AChE and BChE with IC50s of 51.25 μM and 63.07 μM[1]. |
Target | AChE BChE |