Home
Products
Dihydrochelerythrine
| Product Name | Dihydrochelerythrine |
| Price: | $277 / 20mg |
| Catalog No.: | CN01712 |
| CAS No.: | 6880-91-7 |
| Molecular Formula: | C21H19NO4 |
| Molecular Weight: | 349.38 g/mol |
| Purity: | >=98% |
| Type of Compound: | Alkaloids |
| Physical Desc.: | Powder |
| Source: | The herbs of Chelidonium majus |
| Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| SMILES: | COc1c(OC)ccc2c1CN(C)c1c2ccc2c1cc1OCOc1c2 |
| Contact us | |
|---|---|
| First Name: | |
| Last Name: | |
| E-mail: | |
| Question: | |
| Description | Dihydrochelerythrine is a natural compound isolated from the leaves of Macleaya microcarpa; has antifungal activity.IC50 value:Target: in vitro: Dihydrochelerythrine showed the highest antifungal activity against B. cinerea Pers, with 98.32% mycelial growth inhibition at 50 μg/mL. Dihydrochelerythrine inhibited spore germination in vitro in a concentration-dependent manner [1]. Dihydrochelerythrine appeared to be less cytotoxic since the viability of cells exposed to 20 microM dihydrochelerythrine for 24h was reduced only to 53%. A dose-dependent induction of apoptosis and necrosis by chelerythrine and dihydrochelerythrine was confirmed by annexin V/propidium iodide dual staining flow cytometry [2]. Dihydrochelerythrine (4) exhibited strong activity against methicillin-resistant Staphylococcus aureus SK1 and moderate activity against Escherichia coli TISTR 780 with MIC values of 8 and 16 μg/mL, respectively [3]. |
| Density | 1.3±0.1 g/cm3 |
| Boiling Point | 565.9±50.0 °C at 760 mmHg |
| Flash Point | 171.6±27.3 °C |
| Exact Mass | 349.131409 |
| PSA | 40.16000 |
| LogP | 4.56 |
| Vapour Pressure | 0.0±1.5 mmHg at 25°C |
| Storage condition | 2-8℃ |