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Isocucurbitacin D
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Product Name Isocucurbitacin D
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Catalog No.: CN07152
CAS No.: 68422-20-8
Molecular Formula: C30H44O7
Molecular Weight: 516.7 g/mol
Purity: > 95%
Type of Compound: Triterpenoids
Physical Desc.: Powder
Source: The herbs of Trichosanthes cucumeroides
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
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Description Isocucurbitacin D is an antitumor agent[1].
In Vitro Isocucurbitacin D 抑制癌细胞生长,对 SK-MEL-2、A549、XF498、HCT15 和 SK-OV-3 细胞的 ED50 分别为 0.06、0.2、0.6、0.8 和 1.2 μg/mL[1]。 Cell Proliferation Assay[1] Cell Line: MCF-7, MDA MB 231, A2780, A2780 CP, HepG2 and HCT-116 cells Concentration: 0-100 μM Incubation Time: 48 h Result: Inhibited cell proliferation with IC50s of 12.0, 30.7, 37.8, 47.9, >100 and >100 μM against MDA MB 231, HCT-116, HepG2, MCF-7, A2780 and A2780 CP, respectively.
Exact Mass516.30900
PSA132.13000
LogP2.92850