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Product Name | Isocucurbitacin D |
Price: | Inquiry |
Catalog No.: | CN07152 |
CAS No.: | 68422-20-8 |
Molecular Formula: | C30H44O7 |
Molecular Weight: | 516.7 g/mol |
Purity: | > 95% |
Type of Compound: | Triterpenoids |
Physical Desc.: | Powder |
Source: | The herbs of Trichosanthes cucumeroides |
Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
SMILES: |
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Description | Isocucurbitacin D is an antitumor agent[1]. |
In Vitro | Isocucurbitacin D 抑制癌细胞生长,对 SK-MEL-2、A549、XF498、HCT15 和 SK-OV-3 细胞的 ED50 分别为 0.06、0.2、0.6、0.8 和 1.2 μg/mL[1]。 Cell Proliferation Assay[1] Cell Line: MCF-7, MDA MB 231, A2780, A2780 CP, HepG2 and HCT-116 cells Concentration: 0-100 μM Incubation Time: 48 h Result: Inhibited cell proliferation with IC50s of 12.0, 30.7, 37.8, 47.9, >100 and >100 μM against MDA MB 231, HCT-116, HepG2, MCF-7, A2780 and A2780 CP, respectively. |
Exact Mass | 516.30900 |
PSA | 132.13000 |
LogP | 2.92850 |