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6,8-Diprenylnaringenin
| Product Name | 6,8-Diprenylnaringenin |
| Price: | Inquiry |
| Catalog No.: | CN05144 |
| CAS No.: | 68236-11-3 |
| Molecular Formula: | C25H28O5 |
| Molecular Weight: | 408.5 g/mol |
| Purity: | >=98% |
| Type of Compound: | Flavonoids |
| Physical Desc.: | Cryst. |
| Source: | The herbs of Humulus lupulus |
| Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| SMILES: |
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| Description | 6,8-Diprenylnaringenin (Lonchocarpol A; Senegalensin), a hop prenylflavonoid, is a inhibitor of breast cancer resistance protein (BCRP/ABCG2). 6,8-Diprenylnaringenin inhibits ABCG2-mediated efflux of Mitoxantrone, and 3H-Methotrexate transport (IC50=0.41 μM) in HEK293 cells. 6,8-Diprenylnaringenin exhibits some estrogenicity, but its potency is less than 1% of that of 8-Prenylnaringenin[1][2]. |
| Density | 1.22g/cm3 |
| Boiling Point | 639.245°C at 760 mmHg |
| Flash Point | 218.297°C |
| Exact Mass | 408.19400 |
| PSA | 86.99000 |
| LogP | 5.52730 |