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Royleanone
| Product Name | Royleanone |
| Price: | Inquiry |
| Catalog No.: | CN05883 |
| CAS No.: | 6812-87-9 |
| Molecular Formula: | C20H28O3 |
| Molecular Weight: | 316.4 g/mol |
| Purity: | >=98% |
| Type of Compound: | Quinones |
| Physical Desc.: | Powder |
| Source: | The herbs of Salvia prionitis |
| Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| SMILES: |
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| Description | Royleanone, a diterpenoid isolated from plants, inhibits the proliferation of cancer cells by inducing cell cycle arrest and mitochondria-mediated apoptosis, also inhibits cell migration potential, inhibits mTOR/PI3/AKT signaling pathway in LNCaP prostate cancer cells[1]. |
| Target | mTOR/PI3/AKT[1] |
| In Vitro | Royleanone (0-200 μM; 48 h) 以剂量依赖性方式抑制 LNCaP 癌细胞的活力，IC50 为 12.5 μM[1]。 |
| Density | 1.1±0.1 g/cm3 |
| Boiling Point | 426.4±45.0 °C at 760 mmHg |
| Flash Point | 225.8±25.2 °C |
| Exact Mass | 316.203857 |
| PSA | 54.37000 |
| LogP | 6.18 |
| Vapour Pressure | 0.0±2.3 mmHg at 25°C |