Home
Products
Platyconic acid A
| Product Name | Platyconic acid A |
| Price: | Inquiry |
| Catalog No.: | CN07688 |
| CAS No.: | 68051-23-0 |
| Molecular Formula: | C57H90O29 |
| Molecular Weight: | 1239.3 g/mol |
| Purity: | >=98% |
| Type of Compound: | Triterpenoids |
| Physical Desc.: | Powder |
| Source: | The roots of Platycodon grandiflorum |
| Solvent: | DMSO, Pyridine, Methanol, Ethanol, etc. |
| SMILES: |
| Contact us | |
|---|---|
| First Name: | |
| Last Name: | |
| E-mail: | |
| Question: | |
| Description | Platyconic Acid A is an active component of changkil saponins from platycodon grandiflorum and can be used for the research of reducing airway inflammation[1]. |
| In Vitro | Platyconic Acid A (0.5~2 μM; 30 minutes; A549 cells) inhibits PMA-induced NF-κB p65 phosphorylation, IκBα phosphorylation and degradation and Akt phosphorylation in a concentration-dependent manner[1]. Platyconic Acid A (0.5~2 μM; 24 hours; A549 cells) decreases PMA-increased MUC5AC mRNA expression in a concentration-dependent manner[1]. Western Blot Analysis[1] Cell Line: A549 cells Concentration: 0.5~2 μM Incubation Time: 30 minutes Result: Inhibited PMA-induced NF-κB p65 phosphorylation, IκBα phosphorylation and degradation and Akt phosphorylation in a concentration-dependent manner. RT-PCR[1] Cell Line: A549 cells Concentration: 0.5~2 μM Incubation Time: 24 hours Result: Decreased PMA-increased MUC5AC mRNA expression in a concentration-dependent manner. |
| Density | 1.6±0.1 g/cm3 |
| Exact Mass | 1238.556763 |
| LogP | -0.36 |