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Sodium Danshensu
| Product Name | Sodium Danshensu |
| Price: | $31 / 20mg |
| Catalog No.: | CN07027 |
| CAS No.: | 67920-52-9 |
| Molecular Formula: | C9H9O5Na |
| Molecular Weight: | 220.2 g/mol |
| Purity: | >=98% |
| Type of Compound: | Phenylpropanoids |
| Physical Desc.: | Powder |
| Source: | The roots of Salvia miltiorrhiza Bge. |
| Solvent: | DMSO, Pyridine, Methanol, Ethanol, etc. |
| SMILES: | [O-]C(=O)C(Cc1ccc(c(c1)O)O)O.[Na+] |
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| Description | Danshensu (sodium salt) is odium salt of danshensu from the widely used Chinese herb Danshen. It can inhibited phenylephrine- and CaCl2-induced vasoconstriction in Ca2+-free medium.In vitro: Sodium danshensu showed a biphasic effects on vessel tension. While low dosage of sodium danshensu produced small contraction possibly through transient enhancement of Ca2+ influx, high dosage produced significant vasodilation mainly through promoting the opening of non-selective K+ channels and small-conductance calcium-sensitive K+ channels in the vascular smooth muscle cells.[1]In vivo: Danshensu did not change the expression of AGEs but partly blocked the increased expression of RAGE in the hippocampus of diabetic mice. Danshensu could ameliorate the cognitive decline in streptozotocin-induced diabetic mice by attenuating advanced glycation end product-mediated neuroinflammation.[2] |
| Exact Mass | 220.034775 |
| PSA | 100.82000 |
| Storage condition | 2-8°C |