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Product Name | Isorhamnetin 3,7-O-diglucoside |
Price: | $351 / 5mg |
Catalog No.: | CN04438 |
CAS No.: | 6758-51-6 |
Molecular Formula: | C28H32O17 |
Molecular Weight: | 640.6 g/mol |
Purity: | >95% |
Type of Compound: | Flavonoids |
Physical Desc.: | Powder |
Source: | The herbs of Hippophae rhamnoides Linn. |
Solvent: | DMSO, Pyridine, Methanol, Ethanol, etc. |
SMILES: |
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Description | Isorhamnetin 3,7-di-O-β-D-glucopyranoside, a major flavonoid compound, is metabolized in vivo by intestinal bacteria to isorhamnetin and that isorhamnetin plays an important role as an antioxidant[1]. |
In Vivo | Isorhamnetin 3,7-di-O-β-D-glucopyranoside (10 or 20 mg/kg of body weight/day for 10 days; p.o.) to rats with streptozotocin-induced diabetes significantly reduced serum levels of glucose and 5-(hydroxymethyl)furfural (5-HMF), which is glycosylated with hemoglobin and is an indicator of oxidative stress[1]. Animal Model: Male Wistar rats (5 weeks old, 120-130 g) (STZ-induced diabetic rats had higher glucose and 5-HMF levels than normal rats)[1] Dosage: 10 or 20 mg/kg of body weight Administration: P.o.; daily for 10 days Result: The serum glucose levels of rats given 10 and 20 mg of orally were 510.1 and 492.4 mg/dL, respectively, whereas the control level was 574.2 mg/dL. |
Exact Mass | 640.16400 |
PSA | 278.66000 |
Storage condition | -20℃ |