Home
Products
Spathulenol
| Product Name | Spathulenol |
| Price: | Inquiry |
| Catalog No.: | CN09405 |
| CAS No.: | 6750-60-3 |
| Molecular Formula: | C15H24O |
| Molecular Weight: | 220.4 g/mol |
| Purity: | >=98% |
| Type of Compound: | Sesquiterpenoids |
| Physical Desc.: | Oil |
| Source: | The herbs of Salvia sclarea |
| Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| SMILES: | C=C1CC[C@@H]2[C@H]([C@H]3[C@H]1CC[C@]3(C)O)C2(C)C |
| Contact us | |
|---|---|
| First Name: | |
| Last Name: | |
| E-mail: | |
| Question: | |
| Description | Spathulenol is isolated from Psidium guineense Sw, and has antioxidant, anti-inflammatory, antiproliferative and antimycobacterial activities. Spathulenol shows a high antioxidant activity with an IC50 of 85.60 μg/mL in the DPPH system[1]. |
| In Vitro | Spathulenol exhibits a high antioxidant activity s in the DPPH and MDA system, exhibits significant DPPH free radical activity, with IC50 values of 85.60 μg/mL[1]. |
| In Vivo | Spathulenol (oral administration; 300 mg/kg) shows a significant inhibition in the Cg-induced mice paw oedema and pleurisy model[1]. In a spontaneous lipoperoxidation rat brain homogenate model, when incubated in controlled temperature andoxygenation conditions, PG-1 exhibits a high activity with an IC50 value of 26.13 μg/mL, respectively, which iscomparable to a commercial antioxidant BHT (38.41 μg/mL), Thus, PG-1 contributes to a decrease in the generation of MDA,which is a toxic product resulting from the degradation of the cell membrane by lipid peroxidation, causing cell ruptures and mutations[1]. |
| Density | 1.0±0.1 g/cm3 |
| Boiling Point | 297.0±19.0 °C at 760 mmHg |
| Flash Point | 123.9±13.7 °C |
| Exact Mass | 220.182709 |
| PSA | 20.23000 |
| LogP | 4.45 |
| Vapour Pressure | 0.0±1.4 mmHg at 25°C |