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Gomisin J
| Product Name | Gomisin J |
| Price: | $146 / 10mg |
| Catalog No.: | CN02923 |
| CAS No.: | 66280-25-9 |
| Molecular Formula: | C22H28O6 |
| Molecular Weight: | 388.19 g/mol |
| Purity: | >=98% |
| Type of Compound: | Lignans |
| Physical Desc.: | Powder |
| Source: | The fruits of Schizandra chinensis |
| Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| SMILES: | COc1c2c(CC(C)C(Cc3c2c(OC)c(c(c3)O)OC)C)cc(c1OC)O |
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| Description | Gomisin J is a small molecular weight lignan found in Schisandra chinensis and has been demonstrated to have vasodilatory activity[1]. Gomisin J suppresses lipid accumulation by regulating the expression of lipogenic and lipolytic enzymes and inflammatory molecules through activation of AMPK, LKB1 and Ca2+/calmodulin-dependent protein kinase II and inhibition of fetuin-A in HepG2 cells. gomisin J has potential benefits in treating nonalcoholic fatty liver disease[2]. |
| Target | AMPK Ca2+ |
| Density | 1.161 |
| Boiling Point | 587.5±50.0 °C at 760 mmHg |
| Flash Point | 309.1±30.1 °C |
| Exact Mass | 388.188599 |
| PSA | 77.38000 |
| LogP | 4.80 |
| Vapour Pressure | 0.0±1.7 mmHg at 25°C |