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Product Name | Cimicifugoside |
Price: | Inquiry |
Catalog No.: | CN07733 |
CAS No.: | 66176-93-0 |
Molecular Formula: | C37H54O11 |
Molecular Weight: | 674.81 g/mol |
Purity: | >=98% |
Type of Compound: | Triterpenoids |
Physical Desc.: | Powder |
Source: | The roots of Saposhnikovia divaricata |
Solvent: | DMSO, Pyridine, Methanol, Ethanol, etc. |
SMILES: | CC(=O)O[C@@H]1C[C@]23C[C@]43CC[C@@H](C([C@@H]4CC=C2[C@]2([C@@]1(C)[C@H]1[C@H](C)C[C@@]3(O[C@H]1C2)OC([C@@]1([C@H]3O1)C)O)C)(C)C)O[C@@H]1OC[C@H]([C@@H]([C@H]1O)O)O |
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Description | Cimicifugoside, a triterpenoid isolated from Cimicifuga simplex, is a novel specific nucleoside transport inhibitor that displays synergistic potentiation of methotrexate cytotoxicity[1]. Cimicifugoside shows immunosuppressive activity, which is preferentially directed toward B-cell function with larger doses being required for suppression of T-cell function[2]. |
Target | Nucleoside transport[1] |
Density | 1.38 g/cm3 |
Exact Mass | 674.36700 |
PSA | 156.67000 |
LogP | 2.94870 |