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Psoralen
| Product Name | Psoralen |
| Price: | $18 / 20mg |
| Catalog No.: | CN06231 |
| CAS No.: | 66-97-7 |
| Molecular Formula: | C11H6O3 |
| Molecular Weight: | 186.2 g/mol |
| Purity: | >=98% |
| Type of Compound: | Coumarins |
| Physical Desc.: | Powder |
| Source: | The seeds of Psoralea corylifolia L. |
| Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| SMILES: | O=c1ccc2c(o1)cc1c(c2)cco1 |
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| Description | Psoralen(Furocoumarin) is an active ingredient from Fructus Psoraleae; has anticancer activity.IC50 value:Target:in vitro: Psoralen dosages of 1-10 μM exhibited low cytotoxicity toward chondrocytes. However, a dosage of 100 μM suppressed the proliferation of chondrocytes. Different concentrations of psoralen treatments on chondrocytes revealed that GAG and Type II collagen synthesis increased, especially at 100 μM, by 0.39-fold and 0.48-fold, respectively, on day 3, and by 0.51-fold and 0.56-fold, respectively, on day 9 [1]. in vivo: Tumor volume inhibition rates were 43.75% and 40.18%, respectively, in the psoralen and isopsoralen low-dose groups, and tumor weight inhibition rates were 38.83% and 37.77%. Tumor volume inhibition rates were 67.86% and 66.96%, respectively, in the psoralen and isopsoralen high-dose groups, and tumor weight inhibition rates were 49.47% and 47.87% [2]. psoralen can inhibit metastasis of breast cancer to bone in vivo. Histological, molecular biological, and imaging analyses revealed that psoralen inhibits bone metastases in mice [3]. |
| Density | 1.4±0.1 g/cm3 |
| Boiling Point | 362.6±27.0 °C at 760 mmHg |
| Flash Point | 173.1±23.7 °C |
| Exact Mass | 186.031693 |
| PSA | 43.35000 |
| LogP | 1.67 |
| Vapour Pressure | 0.0±0.8 mmHg at 25°C |
| Storage condition | 2-8°C |