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Coleonol B
| Product Name | Coleonol B |
| Price: | $293 / 10mg |
| Catalog No.: | CN08786 |
| CAS No.: | 64657-21-2 |
| Molecular Formula: | C22H34O7 |
| Molecular Weight: | 410.5 g/mol |
| Purity: | >=98% |
| Type of Compound: | Diterpenoids |
| Physical Desc.: | Powder |
| Source: | The herbs of Coleus forskohlii |
| Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| SMILES: |
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| Description | Isoforskolin is the principle active component of C. forskohlii native to China. Isoforskolin reduces the secretion of lipopolysaccharide (LPS)-induced cytokines, namely TNF-α, IL-1β, IL-6 and IL-8, in human mononuclear leukocytes. Isoforskolin acts as an anti-inflammatory agent for the treatment of Lyme arthritis[1]. |
| In Vitro | Isoforskolin downregulates the transcription and expression of TNF-α and IL-6 induced by recombinant Borrelia burgdorferi basic membrane protein A (rBmpA)[1]. |
| Density | 1.2±0.1 g/cm3 |
| Boiling Point | 524.5±50.0 °C at 760 mmHg |
| Flash Point | 173.6±23.6 °C |
| Exact Mass | 410.230438 |
| PSA | 113.29000 |
| LogP | 3.40 |
| Vapour Pressure | 0.0±3.1 mmHg at 25°C |
| Storage condition | −20°C |