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Akuammidine
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Product Name Akuammidine
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Catalog No.: CN01000
CAS No.: 639-36-1
Molecular Formula: C21H24N2O3
Molecular Weight: 352.4 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Powder
Source: The herbs of Rauwolfia vomitoria
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
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Description Akuammidine, isolated from the seeds of Picralima nitida, shows a preference for μ-opioid binding sites with Ki values of 0.6, 2.4 and 8.6 μM at μ-, σ- and κ-opioid binding sites, respectively. Akuammidine possesses anti-inflammatory and anti-asthmatic properties[1][2].
In Vitro Akuammidine treatment decreases the expression of IL-6 in cells[1][2].
Density1.3±0.1 g/cm3
Boiling Point513.0±50.0 °C at 760 mmHg
Flash Point264.0±30.1 °C
Exact Mass352.178680
PSA65.56000
LogP2.99
Vapour Pressure0.0±1.4 mmHg at 25°C