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25-Hydroxycholecalciferol monohydrate
| Product Name | 25-Hydroxycholecalciferol monohydrate |
| Price: | $117 / 20mg |
| Catalog No.: | CN06482 |
| CAS No.: | 63283-36-3 |
| Molecular Formula: | C27H44O2 |
| Molecular Weight: | 400.64 g/mol |
| Purity: | >=98% |
| Type of Compound: | Miscellaneous |
| Physical Desc.: | Powder |
| Source: | From milk. |
| Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| SMILES: | OC1CCC(=C)C(=CC=C2CCCC3(C2CCC3C(CCCC(O)(C)C)C)C)C1.O |
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| Description | Calcifediol (monohydrate) is a major circulating metabolite of vitamin D3, acting as a competitive inhibitor with an apparent Ki of 3.9 μM, suppresses PTH secretion and mRNA (ED50=2 nM). |
| In Vitro | Calcifediol in either liposomes or ethanolic solution has no effect on the release of the proinflammatory cytokine KC from Pseudomonas-infected murine epithelial cells. Treatment of infected, human bronchial 16-HBE cells with Calcifediol liposomes results in a significant reduction in bacterial survival[1]. |
| Boiling Point | 529.2ºC at 760 mmHg |
| Flash Point | 221.4ºC |
| PSA | 40.46000 |
| LogP | 6.73390 |
| Vapour Pressure | 2.07E-13mmHg at 25°C |
| Storage condition | −20°C |