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Kuwanon A
| Product Name | Kuwanon A |
| Price: | $276 / 5mg |
| Catalog No.: | CN04812 |
| CAS No.: | 62949-77-3 |
| Molecular Formula: | C25H24O6 |
| Molecular Weight: | 420.5 g/mol |
| Purity: | >=98% |
| Type of Compound: | Flavonoids |
| Physical Desc.: | Yellow powder |
| Source: | The root barks of Morus alba L. |
| Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| SMILES: | CC(=CCc1c(oc2c(c1=O)c(O)cc(c2)O)c1ccc(c2c1OC(C)(C)C=C2)O)C |
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| Description | Kuwanon A is a flavone derivative isolated from the root barks of the mulberry tree (Morus alba L.); inhibits nitric oxide production with an IC50 of 10.5 μM. |
| Target | IC50: 10.5 μM (nitric oxide)[1] |
| In Vitro | Kuwanon A shows significant inhibitory activity towards the differentiation of 3T3-L1 adipocytes with TG inhibition values of 47.1%. Kuwanon A also shows significant nitric oxide (NO) production inhibitory effects in RAW264.7 cells with an IC50 of 10.5 μM[1]. |
| Cell Assay | RAW264.7 cells are treated with Kuwanon A (3, 10, 20, 30, 100 μM). Cell viability is measured using the MTT assay[1]. |
| Exact Mass | 420.15700 |
| PSA | 100.13000 |
| LogP | 5.26970 |
| Storage condition | 2-8℃ |