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Dihydrolycorine
| Product Name | Dihydrolycorine |
| Price: | $131 / 20mg |
| Catalog No.: | CN01334 |
| CAS No.: | 6271-21-2 |
| Molecular Formula: | C16H19NO4 |
| Molecular Weight: | 289.33 g/mol |
| Purity: | >=98% |
| Type of Compound: | Alkaloids |
| Physical Desc.: | Powder |
| Source: | The bulbus of Lycoris radiata (L. Herit.) Herb |
| Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| SMILES: | O[C@H]1C[C@H]2CCN3[C@H]2[C@@H]([C@@H]1O)c1cc2OCOc2cc1C3 |
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| Description | Dihydrolycorine is isolated from Lycoris radiate Herb with antihypertensive and neuroprotective activities[1]. Dihydrolycorine is an inhibitor of protein synthesis in eukarytic cells by inhibiting the peptide bone formation step[2]. |
| Target | Protein synthesis[2] |
| In Vivo | Dihydrolycorine reduces infarct size, cerebral edema, and myeloperoxidase activity in a rat model of focal cerebral ischemia-reperfusion injury when administered following reperfusion[1]. Dihydrolycorine inhibits methoxamine-induced contraction of isolated rabbit aortic rings and rat anococcygeus muscle with pA2 values of 5.93 and 6.35, respectively[3]. |
| Density | 1.5±0.1 g/cm3 |
| Boiling Point | 460.5±45.0 °C at 760 mmHg |
| Flash Point | 232.3±28.7 °C |
| Exact Mass | 289.131409 |
| PSA | 62.16000 |
| LogP | 0.85 |
| Vapour Pressure | 0.0±1.2 mmHg at 25°C |