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12-O-Methylcarnosic acid
| Product Name | 12-O-Methylcarnosic acid |
| Price: | $234 / 10mg |
| Catalog No.: | CN08305 |
| CAS No.: | 62201-71-2 |
| Molecular Formula: | C21H30O4 |
| Molecular Weight: | 346.46 g/mol |
| Purity: | >=98% |
| Type of Compound: | Diterpenoids |
| Physical Desc.: | Powder |
| Source: | The leaves of Rosmarinus officinalis L. |
| Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| SMILES: | COc1c(O)c2c(cc1C(C)C)CC[C@@H]1[C@@]2(CCCC1(C)C)C(=O)O |
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| Description | 12-O-Methylcarnosic acid (12-Methoxycarnosic acid), a diterpene carnosic acid isolated from the acetone extract of Salvia microphylla, is an active constituent of 5α-reductase inhibition with an IC50 value of 61.7 μM. 12-O-Methylcarnosic acid inhibits proliferation in LNCaP cells. 12-O-Methylcarnosic acid has antioxidant, anti-cancer and antimicrobial activity[1][2]. |
| In Vitro | 12-O-Methylcarnosic acid (12-Methoxycarnosic acid; 5 μM) inhibits androgen-dependent proliferation of LNCaP cells as 66.7%[1]. 12-O-Methylcarnosic acid shows antimicrobial activity against S. aureus at 78 μg/mL[2]. |
| Density | 1.1±0.1 g/cm3 |
| Boiling Point | 505.1±50.0 °C at 760 mmHg |
| Flash Point | 173.3±23.6 °C |
| Exact Mass | 346.214417 |
| PSA | 66.76000 |
| LogP | 5.23 |
| Vapour Pressure | 0.0±1.4 mmHg at 25°C |
| Storage condition | ?20°C |