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Tectoridin
| Product Name | Tectoridin |
| Price: | $31 / 20mg |
| Catalog No.: | CN05472 |
| CAS No.: | 611-40-5 |
| Molecular Formula: | C22H22O11 |
| Molecular Weight: | 462.40 g/mol |
| Purity: | >=98% |
| Type of Compound: | Flavonoids |
| Physical Desc.: | Powder |
| Source: | The rhizomes of Belamcanda chinensis (L.) DC. |
| Solvent: | DMSO, Pyridine, Methanol, Ethanol, etc. |
| SMILES: | OC[C@H]1O[C@@H](Oc2cc3occ(c(=O)c3c(c2OC)O)c2ccc(cc2)O)[C@@H]([C@H]([C@@H]1O)O)O |
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| Description | Tectoridin is a isoflavone isolated from Maackia amurensis. Tectoridin is a phytoestrogen and activates estrogen and thyroid hormone receptors. Tectoridin exerts the estrogenic effects via ER-dependent genomic pathway and GPR30-dependent nongenomic pathway[1][2]. |
| In Vitro | Tectoridin scarcely binds to ER alpha as compared to 17beta-estradiol and genistein[2]. Tectoridin induceds potent estrogenic effects, namely recovery of the population of cells in the S-phase after serum starvation, transactivation of the estrogen response element, and induction of MCF-7 cell proliferation[2]. Tectoridin induces estrogenic effect, and this effect is severely abrogated by treatment with U0126 ( MEK1/2 inhibitor). Tectoridin promotes phosphorylation of ERK1/2, but does not affect phosphorylation of ER alpha at Ser (118). It also increases cellular accumulation of cAMP[2]. |
| Density | 1.6±0.1 g/cm3 |
| Boiling Point | 798.1±60.0 °C at 760 mmHg |
| Flash Point | 279.7±26.4 °C |
| Exact Mass | 462.116211 |
| PSA | 179.28000 |
| LogP | 0.29 |
| Vapour Pressure | 0.0±3.0 mmHg at 25°C |