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5,7,8-Trimethoxycoumarin
5,7,8-Trimethoxycoumarin WeChat WhatsApp
Product Name 5,7,8-Trimethoxycoumarin
Price: $483 / 5mg
Catalog No.: CN06235
CAS No.: 60796-65-8
Molecular Formula: C12H12O5
Molecular Weight: 236.2 g/mol
Purity: >=98%
Type of Compound: Coumarins
Physical Desc.: Powder
Source: The herbs of Viola yedonensis Makino
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
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Description 5,7,8-Trimethoxycoumarin is an anti-Parasite agent with IC50s of 25.5 μM and 57.7 μM against Trypanosoma cruzi and L. amazonensis, respectively[1].
In Vitro 5,7,8-Trimethoxycoumarin (0-100 μM; 72 h) 抑制 Trypanosoma cruzi 和 L. amazonensis 的增殖[1]。 Cell Proliferation Assay[1] Cell Line: Trypanosoma cruzi (epimastigotes) and L. amazonensis (promastigote) Concentration: 1.5, 3.1, 6.2, 12.5, 25, 50 and 100 μM Incubation Time: 72 h Result: Inhibited the proliferation in a dose-dependent manner with IC50s of 25.5 μM and 57.7 μM against Trypanosoma cruzi and L. amazonensis, respectively.
Density1.2±0.1 g/cm3
Boiling Point422.7±45.0 °C at 760 mmHg
Flash Point191.5±28.8 °C
Exact Mass236.068466
PSA57.90000
LogP2.37
Vapour Pressure0.0±1.0 mmHg at 25°C