Home
Products
Chrysosplenetin
| Product Name | Chrysosplenetin |
| Price: | $131 / 10mg |
| Catalog No.: | CN05287 |
| CAS No.: | 603-56-5 |
| Molecular Formula: | C19H18O8 |
| Molecular Weight: | 374.4 g/mol |
| Purity: | >=98% |
| Type of Compound: | Flavonoids |
| Physical Desc.: | Yellow powder |
| Source: | The herbs of Laggera pterodonta |
| Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| SMILES: | COc1cc2oc(c3ccc(c(c3)OC)O)c(c(=O)c2c(c1OC)O)OC |
| Contact us | |
|---|---|
| First Name: | |
| Last Name: | |
| E-mail: | |
| Question: | |
| Description | Chrysosplenetin is one of the polymethoxylated flavonoids in Artemisia annua L. (Compositae) and other several Chinese herbs. Chrysosplenetin inhibits P-gp activity and reverses the up-regulated P-gp and MDR1 levels induced by artemisinin (ART). Chrysosplenetin significantly augments the rat plasma level and anti-malarial efficacy of ART, partially due to the uncompetitive inhibition effect of Chrysosplenetin on rat CYP3A[1]. |
| Target | CYP3A |
| Density | 1.4±0.1 g/cm3 |
| Boiling Point | 615.8±55.0 °C at 760 mmHg |
| Flash Point | 222.7±25.0 °C |
| Exact Mass | 374.100159 |
| PSA | 107.59000 |
| LogP | 2.26 |
| Vapour Pressure | 0.0±1.8 mmHg at 25°C |
| Storage condition | 2-8℃ |