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Glabrol
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Product Name Glabrol
Price: $409 / 10mg
Catalog No.: CN04525
CAS No.: 59870-65-4
Molecular Formula: C25H28O4
Molecular Weight: 392.49 g/mol
Purity: >=98%
Type of Compound: Flavonoids
Physical Desc.: Powder
Source: The roots of Glycyrrhiza uralensis
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
SMILES: CC(=CCc1cc(ccc1O)C1CC(=O)c2c(O1)c(CC=C(C)C)c(cc2)O)C
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Description Glabrol (Compound 1), One isoprenyl flavonoid was isolated from ethanol extract of licorice roots, is a potent and non-competitive Acyl-coenzyme A: cholesterol acyltransferase (ACAT) inhibitor with an IC50 value of 24.6 μM for rat liver microsomal ACAT activity[1].
Target ratACAT:24.6 μM (IC50)
In Vitro Glabrol (Compound 1) decreases cholesteryl ester formation with an IC50 value of 26.0 μM in HepG2 cells[1].
Density1.166g/cm3
Boiling Point600ºC at 760 mmHg
Flash Point204.3ºC
Exact Mass392.19900
PSA66.76000
LogP5.82170