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Product Name | Glabrol |
Price: | $409 / 10mg |
Catalog No.: | CN04525 |
CAS No.: | 59870-65-4 |
Molecular Formula: | C25H28O4 |
Molecular Weight: | 392.49 g/mol |
Purity: | >=98% |
Type of Compound: | Flavonoids |
Physical Desc.: | Powder |
Source: | The roots of Glycyrrhiza uralensis |
Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
SMILES: | CC(=CCc1cc(ccc1O)C1CC(=O)c2c(O1)c(CC=C(C)C)c(cc2)O)C |
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Description | Glabrol (Compound 1), One isoprenyl flavonoid was isolated from ethanol extract of licorice roots, is a potent and non-competitive Acyl-coenzyme A: cholesterol acyltransferase (ACAT) inhibitor with an IC50 value of 24.6 μM for rat liver microsomal ACAT activity[1]. |
Target | ratACAT:24.6 μM (IC50) |
In Vitro | Glabrol (Compound 1) decreases cholesteryl ester formation with an IC50 value of 26.0 μM in HepG2 cells[1]. |
Density | 1.166g/cm3 |
Boiling Point | 600ºC at 760 mmHg |
Flash Point | 204.3ºC |
Exact Mass | 392.19900 |
PSA | 66.76000 |
LogP | 5.82170 |