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1-Methyl-2-undecylquinolin-4(1H)-one
| Product Name | 1-Methyl-2-undecylquinolin-4(1H)-one |
| Price: | Inquiry |
| Catalog No.: | CN00986 |
| CAS No.: | 59443-02-6 |
| Molecular Formula: | C21H31NO |
| Molecular Weight: | 313.5 g/mol |
| Purity: | >=98% |
| Type of Compound: | Alkaloids |
| Physical Desc.: | Powder |
| Source: | The fructus of Evodia rutaecarpa. |
| Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
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| Description | 1-Methyl-2-undecyl-4(1H)-quinolone is a potent, irreversible and selective inhibitor of type B monoamine oxidase (MAO-B). 1-Methyl-2-undecyl-4(1H)-quinolone shows a selective inhibition of MAO-B activity with the IC50 and Ki values of 15.3 μM and 9.91 μM, respectively, but did not inhibit type A MAO (MAO-A) activity. Methyl-2-undecyl-4(1H)-quinolone, as a quinolone alkaloid, is isolated from fresh leaves and fruits of Evodia rutaecarpa HOOK. f. et THOMS[1][2]. |
| Target | MAO-B:15.3 μM (IC50) MAO-B:9.91 μM (Ki) |
| In Vitro | 1-Methyl-2-undecyl-4(1H)-quinolone shows a selective inhibition of MAO-B activity with the IC50 and Ki values of 15.3 μM and 9.91 μM, respectively, but did not inhibit type A MAO (MAO-A) activity[2]. |
| Density | 1.0±0.1 g/cm3 |
| Boiling Point | 419.9±45.0 °C at 760 mmHg |
| Flash Point | 141.0±18.1 °C |
| Exact Mass | 313.240570 |
| PSA | 22.00000 |
| LogP | 7.16 |
| Vapour Pressure | 0.0±1.0 mmHg at 25°C |