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Product Name | Equisetin |
Price: | Inquiry |
Catalog No.: | CN01832 |
CAS No.: | 57749-43-6 |
Molecular Formula: | C22H31NO4 |
Molecular Weight: | 373.49 g/mol |
Purity: | >=98% |
Type of Compound: | Alkaloids |
Physical Desc.: | Powder |
Source: | From Fusarium equiseti |
Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
SMILES: | C/C=C/[C@@H]1C=C[C@H]2[C@H]([C@]1(C)/C(=C1/C(=O)[C@@H](N(C1=O)C)CO)/O)CC[C@H](C2)C |
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Description | Equisetin is an N-methylserine-derived acyl tetramic acid isolated from a terrestrial fungus Fusarium equiseti NRRL 5537[1]. Equisetin is a tetramate-containing natural product with antibiotic and cytotoxic activity[2]. Equisetin inhibits the growth of Gram-positive bacteria and HIV-1 integrase activity but shows no activity against Gram-negative bacteria[3]. Equisetin is a Quorum-sensing inhibitor (QSI) that attenuates QS-regulated virulence phenotypes in P. aeruginosa without affecting the growth of bacterias, serves as a leading compound for the treatment of P. aeruginosa infections[4]. |
Density | 1.187 g/cm3 |
Boiling Point | 513.6ºC at 760 mmHg |
Flash Point | 264.4ºC |
Exact Mass | 373.22500 |
PSA | 77.84000 |
LogP | 2.95920 |