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Product Name | Oroxin A |
Price: | $103 / 20mg |
Catalog No.: | CN05509 |
CAS No.: | 57396-78-8 |
Molecular Formula: | C21H20O10 |
Molecular Weight: | 432.38 g/mol |
Purity: | >=98% |
Type of Compound: | Flavonoids |
Physical Desc.: | Yellow powder |
Source: | The roots of Scutellaria baicalensis. |
Solvent: | DMSO, Pyridine, Methanol, Ethanol, etc. |
SMILES: | OCC1OC(Oc2cc3oc(cc(=O)c3c(c2O)O)c2ccccc2)C(C(C1O)O)O |
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Description | Oroxin A is the major component of an ethanol-water Oroxylum indicum (L.) Kurz (Bignoniaceae) seed extract (OISE), activates peroxisome proliferator-activated receptor γ (PPARγ) by docking into the PPARγ protein ligand-binding domain. Oroxin A exhibits an inhibitory activity against α-glucosidase and an antioxidant capacity[1]. Oroxin A exerts anti-breast cancer effects by inducing ER stress-mediated senescence[2]. |
In Vitro | Oroxin A (0.5- 100 μM; 24 hours) significantly increases the PPARγ transcription level and exhibits the strongest activation with 50 μM in HEK-293t cells[1]. |
Density | 1.6±0.1 g/cm3 |
Boiling Point | 784.0±60.0 °C at 760 mmHg |
Flash Point | 279.0±26.4 °C |
Exact Mass | 432.105652 |
PSA | 170.05000 |
LogP | 0.47 |
Vapour Pressure | 0.0±2.9 mmHg at 25°C |
Storage condition | -20℃ |