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Oroxin A
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Product Name Oroxin A
Price: $103 / 20mg
Catalog No.: CN05509
CAS No.: 57396-78-8
Molecular Formula: C21H20O10
Molecular Weight: 432.38 g/mol
Purity: >=98%
Type of Compound: Flavonoids
Physical Desc.: Yellow powder
Source: The roots of Scutellaria baicalensis.
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
SMILES: OCC1OC(Oc2cc3oc(cc(=O)c3c(c2O)O)c2ccccc2)C(C(C1O)O)O
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Description Oroxin A is the major component of an ethanol-water Oroxylum indicum (L.) Kurz (Bignoniaceae) seed extract (OISE), activates peroxisome proliferator-activated receptor γ (PPARγ) by docking into the PPARγ protein ligand-binding domain. Oroxin A exhibits an inhibitory activity against α-glucosidase and an antioxidant capacity[1]. Oroxin A exerts anti-breast cancer effects by inducing ER stress-mediated senescence[2].
In Vitro Oroxin A (0.5- 100 μM; 24 hours) significantly increases the PPARγ transcription level and exhibits the strongest activation with 50 μM in HEK-293t cells[1].
Density1.6±0.1 g/cm3
Boiling Point784.0±60.0 °C at 760 mmHg
Flash Point279.0±26.4 °C
Exact Mass432.105652
PSA170.05000
LogP0.47
Vapour Pressure0.0±2.9 mmHg at 25°C
Storage condition-20℃