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Isochlorogenic acid C(4,5)
| Product Name | Isochlorogenic acid C(4,5) |
| Price: | $62 / 20mg |
| Catalog No.: | CN06922 |
| CAS No.: | 57378-72-0 |
| Molecular Formula: | C25H24O12 |
| Molecular Weight: | 516.45 g/mol |
| Purity: | >=98% |
| Type of Compound: | Phenylpropanoids |
| Physical Desc.: | Powder |
| Source: | The herbs of Laggera alata |
| Solvent: | DMSO, Pyridine, Methanol, Ethanol, etc. |
| SMILES: | O=C(O[C@H]1[C@H](O)C[C@](C[C@H]1OC(=O)/C=C/c1ccc(c(c1)O)O)(O)C(=O)O)/C=C/c1ccc(c(c1)O)O |
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| Description | 4,5-Dicaffeoylquinic acid ( Isochlorogenic acid C) possesses potent hepatoprotective and anti-HBV effects.IC50 value:Target: Anti-hepatitis natural produce.In vitro: To study anti-hepatitis effect of isochlorogenic acid C, anti-apoptotic and anti-injury properties of test compound were evaluated. The results showed that test compound at concentrations of 10 to 100 μg/ml significantly reduced the caspase-3 and transformed growth factor β1 (TGFβ1) levels of the D-GalN-challenged hepatocytes. Also, test compound improved markedly cell viability of the D-GalN-injured hepatocytes and produced a maximum protection rate of 47.28% at a concentration of 100 μg/ml. Furthermore, test compound significantly inhibited productions of HBsAg and HBeAg. Its maximum inhibitory rates on the HBsAg and HBeAg expressions were 86.93 and 59.79%, respectively. In addition, test compound significantly induced the HO-1 expression of HepG2.2.15 cells [1]. In vivo: |
| Density | 1.6±0.1 g/cm3 |
| Boiling Point | 810.8±65.0 °C at 760 mmHg |
| Flash Point | 274.9±27.8 °C |
| Exact Mass | 516.126770 |
| PSA | 211.28000 |
| LogP | 0.89 |
| Vapour Pressure | 0.0±3.0 mmHg at 25°C |
| Storage condition | -20°C |